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This gradual escalation approach is broadly consistent with titration strategies used for other GLP-1-based therapies already authorised in the UK, such as semaglutide (Wegovy) and tirzepatide (Mounjaro), both of which are subject to NICE technology appraisal guidance and NHS prescribing frameworks

In studies using glutathione supplementation, typical doses range from 250 to 1,000 mg per day, and many supplements on the market typically provide around 500 mg per day

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Milton Prabu S, Renugadevi J, Ramesh Kumar T

however, their precise role in GERD initiation and progression remains debated